About your questions, follow my consideration.
1: No, no is possible create this kind of consideration. We have some material about it but don't have precision.
2: No, because flow simulation use navier-stokes (mass and energy conservation) to solver your problem. The fluid need have inlet and outlet.
3: Yes, Flow Simulation can find the pressure acting on the filter using cutplot and goals.
4: If you get all data about this materials, can be possible.
I hope get help you, have a nice day man.
Thank you Bruno for your answer.
To the point 1.) Is a possible to get any material somewhere? or any document to this solution.