currently listed as an enhancement
533206 Ability to support Rotational Symmetry for Flow Simulation (axi-symmetric axisymmetric 2D 3D )
from a "full supported" method, i would go with a quarter symmetry problem.
then you could check a slice by applying some kind of ideal wall at the cut planes (Where there would normally be fluid).
or with a quarter model, i think 2d could work but you have to deal with the cut boundary.
my suggestion, do some testing with a a full, half, quarter, slice and 2d and compare to make sure your method works.