Under tools - mass properties you can get the center of mass and maybe that can help you get the part centered - but under rotation I would not know how to do the analysis...
Are you asking can you define the imbalance to be corrected through FEA? I think in general the answer would be a resounding "no".
Are you asking how to balance a rotor in the lab/shop? That takes a balance machine, or at least accelerometers/velocimeters at the bearings and access to 3X test weight locations (perhaps 3X on 2 planes).