I move around to different clients on a fairly regular basis and I usually need to use their in house "copy settings wizard" file so that I'm working with the proper parameters for their workflow. I have a number of keyboard shortcuts that I simply cannot work efficiently without. So I end up adding those at each new client.

Here are some of my 'must have' shortcuts.

M = Measure tool

D = Smart dimension

T = Trim entities (sketch)

E = Extend entities (sketch)

H = Show/Hide components (I know I can use tab, but old habits die hard and I do find myself using tab and shift-tab sometimes)

CTRL-SHIFT-S = Save As (an old habit from Photoshop that I use constantly)