Measure should work at high DPI. What settings are you using?
- Windows DPI scaling Setting (RMB your Windows Desktop, Choose Display Settings, and see what is listed under "Change the size of text, apps, and other items.
- What size icons are you using (Tools>Customize> Icon Size)
- What windows version are you using (use the run command and type winver and hit enter. This will tell us which Windows 10 update you are using).
- What resolution is your display (in pixels)?
All settings are default on this PC - none were modified from original.
Scale 250% (Recommended)
3840 x 2160 dots on 15 in diagonal screen
Windows 10 Pro Ver 1709 OS Build 16299.64
At first the double down arrow button didn't seem to be active, and then with the cursor near the right edge of that button it worked!