Is it possible to machine this from an aluminum block?

That would be difficult, and expensive, to drill the holes after bending. It's also very long for a drill bit.

You may need a long drill, and drill before the ends are bent.

Or, drill at angles as a flat pattern, then bend.

Another option is make it a cast part.

No, do as Chris suggested, put holes and csks onto the flat part, then form....forming would require special tooling however.

Ernie,

It is possible to machine from a billet of aluminum (less the 5/16 holes). However, the cost greatly depends on the tolerance of the features/dimensions.

The holes can be pierced with a secondary tool (depending on the tolerance required).

A budgetary quote for such a tool, that would pierce one or two holes at a time, is around $14,000.00

We can send you a formal quote if you send us a detailed part print.

Rick

You really need to rethink your design.